July 27, 2015

It don’t mean a thing if the brain ain’t got that swing



(July 27, 2015)  Like Duke Ellington’s 1931 jazz standard, the human brain improvises while its rhythm section keeps up a steady beat. But when it comes to taking on intellectually challenging tasks, groups of neurons tune in to one another for a fraction of a second and harmonize, then go back to improvising, according to new research led by UC Berkeley.

These findings, reported today in the journal Nature Neuroscience, could pave the way for more targeted treatments for people with brain disorders marked by fast, slow or chaotic brain waves, also known as neural oscillations.

Tracking the changing rhythms of the healthy human brain at work advances our understanding of such disorders as Parkinson’s disease, schizophrenia and even autism, which are characterized in part by offbeat brain rhythms. In jazz lingo, for example, bands of neurons in certain mental illnesses may be malfunctioning because they’re tuning in to blue notes, or playing double time or half time.

“The human brain has 86 billion or so neurons all trying to talk to each other in this incredibly messy, noisy and electrochemical soup,” said study lead author Bradley Voytek. “Our results help explain the mechanism for how brain networks quickly come together and break apart as needed.”

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