August 7, 2012

Neutron scattering explains how myoglobin can perform without water




Neutron scattering explains how myoglobin can perform without water

Understanding will help protein’s potential application in biochemical gas sensors or in state-of-the-art wound dressing.

Proteins do not need to be surrounded by water to carry out their vital biological functions, according to scientists from the Institut de Biologie Structurale (IBS) in Grenoble, the University of Bristol, the Australian National University, the Forschungszentrum Jülich, in Germany and the ILL. In a new paper published in the Journal of the American Chemical Society, the team used a state of the art neutron scattering technique to demonstrate that when myoglobin, an oxygen-binding protein found in the muscle tissue of vertebrates, is enclosed in a sheath of surfactant molecules, it  moves in the same way as when it is surrounded by water. These motions are essential if a protein is to perform its biological function, and their findings make proteins a viable material for use in new wound dressings or even as chemical gas sensors.