August 24, 2012

Tokyo Institute of Technology research: Simplifying genetic codes to look back in time




(Tokyo, 24 August 2012) Tokyo Institute of Technology researchers show simpler versions of the universal genetic code can still function in protein synthesis

Daisuke Kiga and co-workers at the Department of Computational Intelligence and Systems Science at Tokyo Institute of Technology, together with researchers across Japan, have shown that simpler versions of the universal genetic code, created by knocking out certain amino acids, can still function efficiently and accurately in protein synthesis [1]. The researchers conducted experiments altering the genetic codein a test tube. They removed the amino acid tryptophan and discovered that the resulting simplified code could still generate proteins as before. By knocking out individual amino acids and observing the effects, scientists will be able to understand how early primordial organisms may have functioned and evolved.