April 14, 2014

Determining the Translocation of Nanoparticles

Understanding the factors determining the translocation of nanoparticles (NPs) across membranes is the key to designing versatile NPs for applications in nanotechnology and biomedicine. NP functionalization, for example coating with polymers or ligands, can directly change the NP-membrane interaction and open a way to control the NP cytotoxicity and translocation. Now, reporting in Nanotechnology, researchers at the Institute of Chemistry of the Chinese Academy of Sciences in China have revealed the important role of grafted polymers on the NP surface in its translocation through a fluidic membrane channel.