Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have developed a model that makes predictions from which differentiated cells – for instance skin cells – can be very efficiently changed into completely different cell types – such as nerve cells, for example.
This can be done entirely without stem cells. These computer-based instructions for reprogramming cells are of huge significance for regenerative medicine. The LCSB researchers present their results today in the prestigious scientific journal “Stem Cells”. This is the first paper based solely on theoretical, yet practically proven, results of computational biology to be published in this journal. (DOI: 10.1002/stem.1473)