Scientists at the Luxembourg Centre for Systems Biomedicine
(LCSB) of the University of Luxembourg have developed a model that makes predictions
from which differentiated cells – for instance skin cells – can be very
efficiently changed into completely different cell types – such as nerve cells,
for example.
This can be done entirely without stem cells. These
computer-based instructions for reprogramming cells are of huge significance
for regenerative medicine. The LCSB researchers present their results today in
the prestigious scientific journal “Stem Cells”. This is the first paper based
solely on theoretical, yet practically proven, results of computational biology
to be published in this journal. (DOI: 10.1002/stem.1473)