July 31, 2013

Tiny, brightly shining silicon crystals could be safe for deep-tissue imaging



In a new study, the crystals had no toxic effects in non-human primates

Tiny silicon crystals caused no health problems in monkeys three months after large doses were injected, marking a step forward in the quest to bring such materials into clinics as biomedical imaging agents, according to a new study.

The findings, published online July 10 in the journal ACS Nano, suggest that the silicon nanocrystals, known as quantum dots, may be a safe tool for diagnostic imaging in humans. The nanocrystals absorb and emit light in the near-infrared part of the spectrum, a quality that makes them ideal for seeing deeper into tissue than traditional fluorescence-based techniques.