July 25, 2013

Rapamycin: limited anti-aging effects



Substance makes mice live longer, but hardly slows down the aging process

The drug rapamycin is known to increase lifespan in mice. Whether rapamycin slows down aging, however, remains unclear. A team of researchers from the German Center for Neurodegenerative Diseases (DZNE) and the Helmholtz Zentrum München has now found that rapamycin extends lifespan - but its impact on aging itself is limited. The life-extending effect seems to be related to rapamycin’s suppression of tumors, which represent the main causes of death in these mouse strains.