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New findings could help lead to drug treatment to prevent
dangerous genetic heart disease
Using a zebrafish model, scientists have identified a drug
compound that appears to reverse arrhythmogenic cardiomyopathy (ACM), a
hereditary disease and leading cause of sudden death in young people. The
findings, led by investigators at Beth Israel Deaconess Medical Center (BIDMC)
in collaboration with Harvard Stem Cell Institute researchers at Brigham and
Women’s Hospital, provide a key first step in developing new therapies for this
dangerous condition, for which there is currently no preventive treatment.