January 6, 2015

‘Flying Carpet’ Technique Uses Graphene To Deliver One-Two Punch Of Anticancer Drugs




An international team of researchers has developed a drug delivery technique that utilizes graphene strips as “flying carpets” to deliver two anticancer drugs sequentially to cancer cells, with each drug targeting the distinct part of the cell where it will be most effective. The technique was found to perform better than either drug in isolation when tested in a mouse model targeting a human lung cancer tumor.

The researchers also found that an anticancer protein, TRAIL, can serve as an active targeting molecule to bind directly to the surface of cancer cells, which had not been demonstrated previously. The work was done by researchers at North Carolina State University, the University of North Carolina at Chapel Hill, and China Pharmaceutical University (CPU).