January 15, 2015

MIT team enlarges brain samples, making them easier to image

New technique enables nanoscale-resolution microscopy of large biological specimens.

Beginning with the invention of the first microscope in the late 1500s, scientists have been trying to peer into preserved cells and tissues with ever-greater magnification. The latest generation of so-called “super-resolution” microscopes can see inside cells with resolution better than 250 nanometers.