Learning and memory relies on the proper processing of
signals that stimulate neuronal cells within the brain. Researchers at the
Biozentrum of the University of Basel, together with an international team of
scientists, has uncovered an important role for the protein coronin 1 in
cognition and behavior. They found that a lack of coronin 1 in mouse and in man
is associated with poor memory, defective learning and aggressive behavior. The
results, recently published in PLOS Biology, identify a novel risk factor for
neurobehavioral dysfunction and reveal a molecular pathway involved in
transferring information within neurons.