June 11, 2014

DNA-Linked Nanoparticles Form Switchable "Thin Films" on a Liquid Surface



Possible pathway to adjustable filters, surfaces with variable mechanical response, or even new ways to deliver genes for biomedical applications

Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new first—the formation of a single layer of nanoparticles on a liquid surface where the properties of the layer can be easily switched. Understanding the assembly of such nanostructured thin films could lead to the design of new kinds of filters or membranes with a variable mechanical response for a wide range of applications. In addition, because the scientists used tiny synthetic strands of DNA to hold the nanoparticles together, the study also offers insight into the mechanism of interactions of nanoparticles and DNA molecules near a lipid membrane. This understanding could inform the emerging use of nanoparticles as vehicles for delivering genes across cellular membranes.