Lymphangiogenesis is a highly regulated process involved in
the pathogenesis of disease. Current in vivo models to assess lymphangiogenesis
are largely unphysiologic. The zebrafish is a powerful model system for
studying development, due to its rapid growth and transparency during early
stages of life. Identification of a network of trunk lymphatic capillaries in
zebrafish provides an opportunity to quantify lymphatic growth in vivo.
journal reference (open access): PLoS ONE >>