September 20, 2012

Self-formign biological scaffolding



A model system that can interpret the role of cross-linking proteins

A new model system of the cellular skeletons of living cells is akin to a mini-laboratory designed to explore how the cells’ functional structures assemble. A paper about to be published in EPJ E by physicist Volker Schaller and his colleagues from the Technical University Munich, Germany, presents one hypothesis concerning self-organisation. It hinges on the findings that a homogeneous protein network, once subjected to stresses generated by molecular motors, compacts into highly condensed fibres.