New heart
failure trigger could change the way cardiovascular drugs are made
July 18,
2012
In their
quest to treat cardiovascular disease, researchers and pharmaceutical companies
have long been interested in developing new medicines that activate a heart
protein called APJ. But researchers at Sanford-Burnham Medical Research
Institute and the Stanford University School of Medicine have now uncovered a
second, previously unknown, function for APJ—it senses mechanical changes when
the heart is in danger and sets the body on a course toward heart failure.
read more: