New
technology provides a deep view into protein structures
09.07.2012
Proteins
usually carry out their biological function when their polypeptide chain is
arranged into a stable three-dimensional structure. The specific structure of a
protein is stabilized by numerous hydrogen bonds that connect individual amino
acids. Using an innovative method, namely Nuclear Magnetic Resonance (NMR)
spectroscopy in combination with high pressure, Dr. Nisius and Prof. Grzesiek
from the Biozentrum of the University of Basel have provided important new
insights into the hydrogen bond network of Ubiquitin and its importance for the
stability of this model protein. Their findings have now been published in the
renowned scientific journal Nature Chemistry.
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