July 2, 2012

BEYOND BASE-PAIRS: MAPPING THE FUNCTIONAL GENOME




BEYOND BASE-PAIRS: MAPPING THE FUNCTIONAL GENOME

Regulatory Sequences of Mouse Genome Sequenced for First Time

New York, NY and San Diego, Calif., July 1, 2012 -  Popularly dubbed “the book of life,” the human genome is extraordinarily difficult to read. But without full knowledge of its grammar and syntax, the genome’s 2.9 billion base-pairs of adenine and thymine, cytosine and guanine provide limited insights into humanity’s underlying genetics.

In a paper published online in the July 1 issue of the journal Nature, researchers at the Ludwig Institute for Cancer Research and the University of California, San Diego School of Medicine open the book further, mapping for the first time a significant portion of the functional sequences of the mouse genome, the most widely used mammalian model organism in biomedical research.

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