September 11, 2013

How Chromosome Ends Influence Cellular Aging



Heidelberg researchers study the function of telomeres in cellular aging processes

By studying processes that occur at the ends of chromosomes, a team of Heidelberg researchers has unravelled an important mechanism towards a better understanding of cellular aging. The scientists focused on the length of the chromosome ends, the so-called telomeres, which can be experimentally manipulated. Their research, which was conducted at the Center for Molecular Biology of Heidelberg University (ZMBH), allows for new approaches in the development of therapies for tissue loss and organ failure associated with senescence (cellular aging). The research results may also be significant for cancer treatment. They were recently published in the journal “Nature Structural & Molecular Biology”.