Experiments with neutrons at the Technische Universität
München (TUM) show that the antidepressant lithium accumulates more strongly in
white matter of the brain than in grey matter. This leads to the conclusion
that it works differently from synthetic psychotropic drugs. The tissue samples
were examined at the Research Neutron Source Heinz Maier-Leibnitz (FRM II) with
the aim of developing a better understanding of the effects this substance has
on the human psyche.
At present lithium is most popular for its use in
rechargeable batteries. But for decades now, lithium has also been used to
treat various psychological diseases such as depressions, manias and bipolar
disorders. But, the exact biological mode of action in certain brain regions
has hardly been understood. It is well known that lithium lightens moods and
reduces aggression potential.