September 26, 2013

Without a trace - Cells keep to one direction by erasing the path




Migrating cells, it seems, cover their tracks not for fear of being followed, but to keep moving forward. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have now shown that cells in a zebrafish embryo determine which direction they move in by effectively erasing the path behind them. The findings, published online today in Nature, could have implications not just for development but also for cancer and metastasis.