September 19, 2013

TINY BOTTLES AND MELTING CORKS: TEMPERATURE REGULATES A NEW DELIVERY SYSTEM FOR DRUGS AND FRAGRANCES

Close-up view of the tiny bottles.
click on image to enlarge

Microscopic, bottle-like structures with corks that melt at precisely-controlled temperatures could potentially release drugs inside the body or fragrances onto the skin, according to a recently published study.

Typical drug delivery systems act more like sponges than bottles. For example, drugs are absorbed into polymer particles and then allowed to diffuse out over time. The researchers hope that the new system may allow for greater control of drug delivery. Cargo would stay inside the hollow polymer particle when plugged with a solid cork. When the cork is melted by body heat, the drugs would quickly flow out of the particle bottle.