October 2, 2012

Animals engineered with pinpoint accuracy




More accurate genetic modification has created allergen-free cow's milk and pigs that could serve as a model for atherosclerosis.

Two genetically engineered farm animals reported today illustrate how far from Frankenstein’s stitched-together monster animal biotechnology has come. One of those animals, a cow, secretes milk that lacks an allergy-inducing protein because researchers accurately blocked its production using the technique of RNA interference1. And in pigs, scientists have used an enzyme called a TALEN2 to scramble a gene that would normally help remove cholesterol.