May 21, 2013

Single-Cell Transfection Tool Enables Added Control for Biological Studies




McCormick researchers develop method of delivering molecules into targeted cells

Northwestern University researchers have developed a new method for delivering molecules into single, targeted cells through temporary holes in the cell surface. The technique could find applications in drug delivery, cell therapy, and related biological fields.

Bulk electroporation — a technique used to deliver molecules into cells through reversible nanopores in the cell membrane that are caused by exposing them to electric pulses — is an increasingly popular method of cell transfection. (Cell transfection is the introduction of molecules, such as nucleic acids or proteins, into a cell to change its properties.)