UCI study also identifies possible gene target linked to
cognitive disabilities
UC Irvine neurobiologists have found a novel molecular
mechanism that helps trigger the formation of long-term memory. The researchers
believe the discovery of this mechanism adds another piece to the puzzle in the
ongoing effort to uncover the mysteries of memory and, potentially, certain
intellectual disabilities.
In a study led by Marcelo Wood of UC Irvine’s Center for the
Neurobiology of Learning & Memory, the team investigated the role of this
mechanism – a gene designated Baf53b – in long-term memory formation. Baf53b is
one of several proteins making up a molecular complex called nBAF.