IRB Barcelona scientists pave the way towards describing the
conformation of proteins that do not have a defined structure
Structural and theoretical techniques are combined to
develop new methodologies for the analysis of proteins
Researchers with the joint program between IRB Barcelona and
the Barcelona Supercomputing Center (BSC) have devised a new strategy to study
the shape of proteins. This study has been led by Modesto Orozco, head of the
Molecular Modeling and Bioinformatics Group, and Xavier Salvatella, head of the
Molecular Biophysics Group, both ICREA scientists at IRB Barcelona. According
to Orozco, also senior professor of the University of Barcelona and director of
the Life Sciences Department at BSC, “by combining computational modeling and
experimental physicochemical techniques, we have revealed the structures of
proteins, which, until now, were unachievable because of technical barriers”.
The results are available from today in the electronic version of the
prestigious journal Proceedings of the National Academy of Sciences (PNAS)