Dormancy of
stem cells enables them to remain viable…many days post mortem
Under the
direction of Fabrice Chrétien*, in collaboration with Shahragim Tajbakhsh**,
researchers from the Institut Pasteur, the Université de Versailles
Saint-Quentin-en-Yvelines, the Paris Public Hospital Network (AP-HP), and the
CNRS have shown for the first time in humans and mice, the capacity of stem
cells to adopt a dormant state when their environment becomes hostile,
including several days after death. This ability to significantly reduce
metabolic activity enables them to preserve their potential for cellular
division, even after extended periods post mortem. After isolation, they can
then be used to repair damaged organs or tissues. This discovery could lead to
new therapeutic avenues for treating numerous diseases. The study is being
published today in the journal Nature communications.
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