(June 22, 2015) Medical science is placing high hopes on nanoparticles as in future they could be used, for example, as a vehicle for targeted drug delivery. In collaboration with an international team of researchers, scientists at the Helmholtz Zentrum München and the University of Marburg have for the first time succeeded in assaying the stability of these particles and their distribution within the body. Their results, which have been published in the journal Nature Nanotechnology, show that a lot of research is still needed in this field.
Nanoparticles are the smallest particles capable of reaching virtually all parts of the body. Researchers use various approaches to test ways in which nanoparticles could be used in medicine – for instance, to deliver substances to a specific site in the body such as a tumor. For this purpose, nanoparticles are generally coated with organic materials because their surface quality plays a key role in determining further targets in the body. If they have a water-repellent shell, nanoparticles are quickly identified by the body’s immune system and eliminated.